07-07-2011, 01:01 AM
Of course, we can debate the meaning of "significant" 
Statistically speaking, it simply means a result which could not have been achieved by chance. That is, if you compare a new intermediate with the M855 in terms of their average barrier penetration or gel test permanent channel size, the new intermediate should be clearly superior.
Barrier penetration can be quantified more precisely, but gel test channels are more difficult since it's not just the volume of the permanent channel which matters but the distance at which it reaches its maximum width.
Statistically speaking, it simply means a result which could not have been achieved by chance. That is, if you compare a new intermediate with the M855 in terms of their average barrier penetration or gel test permanent channel size, the new intermediate should be clearly superior.
Barrier penetration can be quantified more precisely, but gel test channels are more difficult since it's not just the volume of the permanent channel which matters but the distance at which it reaches its maximum width.