Going to Wyoming in October for a Cow Elk, with my 6.5 Grendel.

[tdbru]

Good luck A2. having taken quite a few cow elk when i lived in AZ, elk can be some tough critters. i'd recommend getting as close as you can before the shot. shot placement is always key, regardless of caliber, but with the Gr. your margin for error is not the same as your 30-06 margin of error. but i'm sure you know all this anyway. just don't be surprised if you have a long tracking job for recovery. i hope it drops in it's tracks for you. long tracking jobs are never fun.
-tdbru